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Research - TCH - Medical Oncology - Clinical trials

Clinical trials

PACT: Preferences for adjuvant chemotherapy (ACT) in non-small-cell lung cancer: What makes it worthwhile to patients and their doctors?Observational cohort study of patients, surgeons and oncologists

Symptom Benefit: Does Palliative Chemotherapy Improve Symptoms in Women with Recurrent Ovarian Cancer? Measuring subjective improvement as well as objective response to estimate the benefit of palliative chemotherapy in women with platinum resistant or refractory ovarian cancer (ANZGOG-0701/GCIG)

SORCE (RE05):A phase III randomised double blind study comparing sorafenib with placebo in patients with resected primary renal cell carcinoma at high or intermediate risk of relapse.

BRAIN TRAIN: Evaluation of a Cognitive Rehabilitation Programme in Cancer Survivors with Self Reported Cognitive Impairment

SCOT: Short Course Oncology Therapy-A study of adjuvant chemotherapy in colorectal cancer (12 weeks versus 24 weeks oxaliplatin and 5FU).

TRACC:Prospective Study of clinical outcomes and analysis of bevacizumab use in metastatic colorectal cancer: BioGrid Project

PAN01:A randomised phase II study evaluating potential predictive biomarkers in the treatment of metastatic pancreatic cancer.

GAP: Phase II study of Gemcitabine and nab-Paclitaxel for Resectable Pancreas Cancer.

RESILIENCE: A phase III randomised, double blind, placebo-controlled trial comparing plus sorafenib versus capecitabine plus placebo in the treatment of locally advanced or metastatic HER2-negative breast cancer.

PICASSO III: A phase III multicentre, international, radomised, double blind, placebo controlled study of doxorubicin plus palifosfamide-tris versus doxorubicin plus placebo in patients with front-line metastatic soft tissue sarcoma.

PROSELICA: Randomised, open label study comparing cabizitaxel at 20 mg/sqm and at 25 mg/sqm every 3 weeks in combintation with prednisone for the treatment of metastatic castrate resistant prostate cancer previously treated with a docetaxel containing regimen.

ctDNA: Circulating Tumour DNA as a Marker of Occult Disease in Stage II Colorectal Cancer and Response to Therapy in Metastatic Colorectal cancer.

ASCENT: An Australian Translational Study to Evaluate the Prognostic Role of Inflammatory Markers in Patients with Metastatic Colorectal Cancer Treated with Bevacizumab (Avastin TM).

INTEGRATE: A Randomised Phase II Double-Blind Placebo-Controlled Study of Regorafenib in Refractory Advanced Oesophago-Gastric Cancer (AOGC)

CATCHEZ:Continuous Access to advanced and metastatic renal cell Carcinoma therapy with Everolimus post pazopanib treatment

Clinical Research Staff

Olive Doig, RN, Clinical Trials Manager.
Anne Ryan, RN, Clinical Trials Coordinator
Jody Berry, RN, Clinical Trials Coordinator
Jillian Harrison, Administrative Assistant
Penny Briese BSc, Administrative Assistant

Phone (02) 6244 3688.

Collaborative Associates

Dr Christine Hemmings RGON, BHB, MBChB, FRCPA, ACT Pathology.

Dr Douglas Taupin, PhD FRACP, Department of Gastroenterology, Canberra Hospital.

Dr Anneke Blackburn, BSc PhD, John Curtin School of Medical Research

Research Grants Held

Prof R. Stuart-Harris. Prospective evaluation of cognitive impairment in women receiving adjuvant chemotherapy for early breast cancer. The Canberra Region Medical Foundation

Stuart-Harris R. The Development of a Clinical Palliative Index for the Treatment of Advanced Cancer. The Private Practice Fund, The Canberra Hospital

Stuart-Harris R. Coping Styles and Severity of Toxicity from Adjuvant Chemotherapy for Early Breast Cancer or Colorectal Cancer. Cancer Council ACT.

Yip D. A Cancer Clinical Trials Research Programme in the ACT. Cancer Council ACT.

Yip D, Budge M, Taupin D, Nolan C. Installation and implementation of Bio21:MMIM (Molecular Medicine Informatics Model now known as BioGrid Australia) in Canberra. TCH Radiation Oncology Private Practice Trust Fund.

Haydon A, Zalcberg J, Walpole E, Yip D, Price T, Howard K, Jefford M. Short Course Oncology Therapy- A study of Adjuvant Chemotherapy in Colorectal Cancer by the CACTUS and OCTO Groups. Cancer Australia Priority driven Collaborative Cancer Research Scheme.

Yip D, Dahlstrom J, Jain S, Barry P, Carpenter J, Clarke C. Westmead Millenium Institute, University of Sydney. The Breast Cancer Tissue Bank: establishment of collection site for collection, storage and transfer of human blood and tissue samples in the ACT.

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