See the current studies perfromed by the Intensive Care Unit at Canberra Hospital and Health Services.
Intensive Care Research - Current Studies
- ARISE is a multicentre randomised controlled trial of early goal directed therapy in patients admitted to ED with severe sepsis. Early goal directed therapy is compared to standard care for septic patients including fluids and inotropes.
- BLISS is a sub-study of ARISE investigating the presence of DNA from bacteria in septic patientís blood. This study is looking at inflammatory and genetic markers of sepsis.
- BLING II is a phase IIb randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients.
- CLAB study is looking at the incidence of blood stream infection in patients who have had a central venous catheter during their stay in ICU.
- DAHLIA is a randomised, double-blind, multi-centre placebo controlled trial of dexmedetomidine for ventilated patients with agitation and delirium in the intensive care unit.
- EPO-TBI is a large multi-centre randomised controlled trial of Erythropoietin in patients with moderate to severe traumatic brain injuries.
- HEAT is a study looking at permissive hyperthermia through avoidance of Paracetamol in known or suspected infection in ICU.
- TRANSFUSE is an ICU multicentre trial comparing the use of the freshest blood for transfusion with the current practice of giving the blood that is next to expire.
- POINT PREVALENCE PROGRAM is a project that all ICUs across Australia and New Zealand are encouraged to participate in to investigate work practice in ICU on a set day.
- IMT is a study that aims to determine whether specific exercises for the breathing muscles shortens the time to breathing without a ventilator in patients who are mechanically ventilated for more than 1 week.
- GSK IV is an open label trial looking at the use of intravenous Zanamivir for patients who test positive to Influenza A or B on PCR.
- RECLAIM II is a double blind, double dummy new study looking at the use of a group of antibiotics, Meropenem, Ceftazidime Avibactum and Flagyl to treat complicated intra-abdominal infections post-operatively.