BioGrid: BioGrid Federated Database for the Installation and Implementation of a Database Node for Bio21 Molecular Medicine Informatics Model
ALT GIST: A Randomised Phase II Trial of Imatinib alternating with Regorafenib compared to Imatinib alone for the first line treatment advanced gastro-intestinal stromal tumour
ELIMINATE: Oestrogen lowering intervention may increase neoadjuvant therapy efficacy. Randomised Phase II trial of neoadjuvant chemotherapy +/- concurrent aromatase inhibitor endocrine therapy to downstage large oestrogen receptor positive breast cancer
Gilead GS-US-296-1080: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-5745 Combined with mFOLFOX6 as First Line Treatment in Patients with Advanced Gastric or Gastroesophageal Junction Adenocarcinoma.
CHECKMATE 227: An Open-Label, Randomised Phase 3 trial of Nivolumab, or Nivolumab plus Ipilimumab versus Platinum Doublet Chemotherapy in Subjects with Chemotherapy-Naïve Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)
BR.31: A Phase III Prospective Double Blind Placebo Controlled Randomized Study of Adjuvant MED14736 in Completely Resected Non-Small Cell Lung Cancer
PROSPER: A Phase 4, Randomized, Double-Blind, Placebo Controlled Study of Continued Enzalutamide Treatment beyond Progression in Patients with Chemotherapy-Naïve, Metastatic-Castration Resistant Prostate Cancer:
ReKindle: Testing an online resource to promote sexual wellbeing for both patients and their partners
TABITHA: Study of the clinical outcomes and analysis of antiHER2 therapy use in treatment of metastatic HER2 positive breast cancer
Genetic and cellular analysis of autoimmune and inflammatory disease: Investigation of immune modulating cancer treatments
ECHO: A Phase III randomised controlled trial of exercise during chemotherapy for patients commencing first line treatment for ovarian cancer.
Cardiometabolic Risk Factor: The prevalence of weight gain and cardiometabolic disease in women with breast cancer: identifying trends from diagnosis to remission
Heart Failure: Early identification of developing cardiac failure in women undergoing chemotherapy with trastuzumab or anthracyclines.
TRACC: Prospective Study of clinical outcomes and analysis of bevacizumab use in metastatic colorectal cancer: BioGrid Project
A biomarker study to develop a multicomponent diagnostic screen for the detection of circulating tumour cells (CTC) and cancer stem cells (CSC) using peripheral blood
Mitotane: Mitotane Pharmacodynamics in Adrenocortical Cancer in Children and Adults
Complete Freund’s Adjuvant: Phase I Study of Complete Freund’s Adjuvant (CFA) in Patients with Refractory and Relapsed Solid Tumours
DYNAMIC: Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Stage II Colorectal Cancer
CHECKMATE 401: A Clinical Trial of Nivolumab (BMS-936558) Combined with Ipilumumab Followed by Nivolumab Monotherapy as First-Line Therapy of Subjects with Histologically Confirmed Stage III (Unresectable) or Stage IV Melanoma
Clinical Research Staff
Dr Yu Jo Chua, Director, Medical Oncology Research Unit
Olive Doig, RN, Clinical Trials Manager.
Anne Ryan, RN, Clinical Trials Coordinator
Rabecca Walker RN, Clinical Trials Coordinator
Edward Craft, Administrative Assistant
Phone (02) 6244 3688.
A/Professor Christine Hemmings RGON, BHB, MBChB, FRCPA, St John of God Pathology, Subiaco WA.
Dr Alesia Ivashkevich, MSc, PhD, Cancer Research Laboratory, Department of Radiation Oncology, Canberra Hospital.
Dr Anneke Blackburn, BSc PhD, John Curtin School of Medical Research
Professor Sudha Rao, BSc PhD, Molecular and Cellular Biology, Centre for Research in Therapeutics Solutions, University of Canberra
A/Professor Kate Pumpa,BSc MSc PhD, Sport and Exercise Science, Faculty of Health, University of Canberra.
Professor Afaf Girgis, Translation Cancer Research Centre, Ingham Insitute for Applied Medical Research, University of NSW.
Research Grants Held
Prof R. Stuart-Harris. Prospective evaluation of cognitive impairment in women receiving adjuvant chemotherapy for early breast cancer. The Canberra Region Medical Foundation
Stuart-Harris R. The Development of a Clinical Palliative Index for the Treatment of Advanced Cancer. The Private Practice Fund, The Canberra Hospital
Stuart-Harris R. Coping Styles and Severity of Toxicity from Adjuvant Chemotherapy for Early Breast Cancer or Colorectal Cancer. Cancer Council ACT.
Yip D. A Cancer Clinical Trials Research Programme in the ACT. Cancer Council ACT.
Yip D, Budge M, Taupin D, Nolan C. Installation and implementation of Bio21:MMIM (Molecular Medicine Informatics Model now known as BioGrid Australia) in Canberra. TCH Radiation Oncology Private Practice Trust Fund.
Haydon A, Zalcberg J, Walpole E, Yip D, Price T, Howard K, Jefford M. Short Course Oncology Therapy- A study of Adjuvant Chemotherapy in Colorectal Cancer by the CACTUS and OCTO Groups. Cancer Australia Priority driven Collaborative Cancer Research Scheme.
Yip D, Dahlstrom J, Jain S, Barry P, Carpenter J, Clarke C. Westmead Millenium Institute, University of Sydney. The Breast Cancer Tissue Bank: establishment of collection site for collection, storage and transfer of human blood and tissue samples in the ACT.
Rao S, Jans D, Forward J, Dahlstrom J, Yip D. Epigenetic regulation by PKC-theta in human breast cancer stem cells. NHMRC Project Grant
Scott R, Balleine R,Clarke C, Dahlstrom J, Forbes J, Marsh D, Pathmanathan N, Simpson P,Yip D, Zeps N. Extending the strategic importance of the Australian Breast Cancer Tissue Bank to facilitate breast cancer research. National Breast Cancer Foundation National Infrastructure Grant
Identification of Melanoma Circulating Tumour Cells (CTC)/Cancer Stem Cells (CSC) burden and the role of novel epigenetic enzymes in melanoma cancer biology