Clinical trials

BioGrid: BioGrid Federated Database for the Installation and Implementation of a Database Node for Bio21 Molecular Medicine Informatics Model

ALT GIST: A Randomised Phase II Trial of Imatinib alternating with Regorafenib compared to Imatinib alone for the first line treatment advanced gastro-intestinal stromal tumour

ELIMINATE: Oestrogen lowering intervention may increase neoadjuvant therapy efficacy. Randomised Phase II trial of neoadjuvant chemotherapy +/- concurrent armoatase inhibitor endocrine therapy to down stage large oestrogen receptor positive breast cancer

PROSPER: A Phase 4, Randomized, Double-Blind, Placebo Controlled Study of Continued Enzalutamide Treatment beyond Progression in Patients with Chemotherapy-Naïve, Metastatic-Castration Resistant Prostate Cancer:

P3BEP: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for participants with intermediate and poor-risk metastatic germ cell tumours

ReKindle: Testing an online resource to promote sexual wellbeing for both patients and their partners

TABITHA: Study of the clinical outcomes and analysis of antiHER2 therapy use in treatment of metastatic HER2 positive breast cancer

Genetic and cellular analysis of autoimmune and inflammatory disease: Investigation of immune modulating cancer treatments

ECHO: A Phase III randomised controlled trial of exercise during chemotherapy for patients commencing first line treatment for ovarian cancer.

Cardiometabolic Risk Factor: The prevalence of weight gain and cardiometabolic disease in women with breast cancer: identifying trends from diagnosis to remission

Heart Failure: Early identification of developing cardiac failure in women undergoing chemotherapy with trastuzumab or anthracyclines.

Coping Together: A study to help couples manage a recent cancer diagnosis

TRACC: Prospective Study of clinical outcomes and analysis of bevacizumab use in metastatic colorectal cancer: BioGrid Project

Mitotane: Mitotane Pharmacodynamics in Adrenocortical Cancer in Children and Adults

Clinical Research Staff

Dr Yu Jo Chua, Director, Medical Oncology Research Unit

Olive Doig, RN, Clinical Trials Manager.
Anne Ryan, RN, Clinical Trials Coordinator
Rabecca Walker RN, Clinical Trials Coordinator
Edward Craft, Administrative Assistant

Phone (02) 6244 3688.

Collaborative Associates

A/Professor Christine Hemmings RGON, BHB, MBChB, FRCPA, St John of God Pathology, Subiaco WA.

Dr Alesia Ivashkevich, MSc, PhD, Cancer Research Laboratory, Department of Radiation Oncology, Canberra Hospital.

Dr Anneke Blackburn, BSc PhD, John Curtin School of Medical Research

Professor Sudha Rao, BSc PhD, Molecular and Cellular Biology, Centre for Research in Therapeutics Solutions, University of Canberra

A/Professor Kate Pumpa,BSc MSc PhD, Sport and Exercise Science, Faculty of Health, University of Canberra.

Professor Afaf Girgis, Translation Cancer Research Centre, Ingham Insitute for Applied Medical Research, University of NSW.

Research Grants Held

Prof R. Stuart-Harris. Prospective evaluation of cognitive impairment in women receiving adjuvant chemotherapy for early breast cancer. The Canberra Region Medical Foundation

Stuart-Harris R. The Development of a Clinical Palliative Index for the Treatment of Advanced Cancer. The Private Practice Fund, The Canberra Hospital

Stuart-Harris R. Coping Styles and Severity of Toxicity from Adjuvant Chemotherapy for Early Breast Cancer or Colorectal Cancer. Cancer Council ACT.

Yip D. A Cancer Clinical Trials Research Programme in the ACT. Cancer Council ACT.

Yip D, Budge M, Taupin D, Nolan C. Installation and implementation of Bio21:MMIM (Molecular Medicine Informatics Model now known as BioGrid Australia) in Canberra. TCH Radiation Oncology Private Practice Trust Fund.

Haydon A, Zalcberg J, Walpole E, Yip D, Price T, Howard K, Jefford M. Short Course Oncology Therapy- A study of Adjuvant Chemotherapy in Colorectal Cancer by the CACTUS and OCTO Groups. Cancer Australia Priority driven Collaborative Cancer Research Scheme.

Yip D, Dahlstrom J, Jain S, Barry P, Carpenter J, Clarke C. Westmead Millenium Institute, University of Sydney. The Breast Cancer Tissue Bank: establishment of collection site for collection, storage and transfer of human blood and tissue samples in the ACT.

Rao S, Jans D, Forward J, Dahlstrom J, Yip D. Epigenetic regulation by PKC-theta in human breast cancer stem cells. NHMRC Project Grant

Scott R, Balleine R,Clarke C, Dahlstrom J, Forbes J, Marsh D, Pathmanathan N, Simpson P,Yip D, Zeps N.  Extending the strategic importance of the Australian Breast Cancer Tissue Bank to facilitate breast cancer research. National Breast Cancer Foundation National Infrastructure Grant